Primary Job Title Entrepreneur in Residence Primary Organization Apple Tree Partners
Location San Francisco, California, United States Regions San Francisco Bay Area, West Coast, Western US Gender Male
Investor Type
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Phil Patten joined DiCE Molecules as chief scientific officer in May 2014. Prior to DiCE Molecules, Phil Patten served at Pioneer HiBred, where he was a DuPont Fellow, research director and led a team of 90 scientists doing directed evolution of proteins and large-scale synthetic biology in the agricultural space. Prior to Pioneer HiBred, Phil
Patten served as senior vice president of biology at Achaogen, where he led the DTRA-funded LpxC program to the discovery of ACHN-975, a small molecule now in Phase 1b with several backup clinical compounds. In addition, he also served as vice president of technology at Maxygen, a pioneer in the field of directed protein evolution via gene shuffling. While at Maxygen, he led the team that produced an improved gene shuffled interferon alpha that entered clinical trials. He is also a named inventor on an evolved herbicide tolerance gene (GAT) that is in late-stage commercial development.
Phil Patten has been actively involved in the practice of directed evolution since the inception of the field in the early 1980s and he holds more than 80 granted patents in this field. He received his Ph.D. in biology from Stanford University and conducted his postdoctorate education in chemistry at the University of California Berkeley. He received his Bachelor of Science degree in biology from CalTech.



