Gender Male
David A. Roth, M.D. serves as senior vice president of clinical development and medical affairs at Infinity.
In this role, he leads the company’s clinical development organization and clinical operations and is also responsible for overseeing the medical affairs function.
Prior to joining Infinity in September 2013, Dr. Roth spent over ten
years with Pfizer Inc. and Wyeth Pharmaceuticals where he contributed to the successful regulatory approval of several products, including Bosulif® (bosutinib), a dual Src/Abl tyrosine kinase inhibitor for the treatment of chronic myelogenous leukemia; Xyntha® and ReFacto AF® for the treatment of hemophilia A; and BeneFIX® for the treatment of hemophilia B. Dr. Roth also led the early development of palbociclib, a CDK 4/6 inhibitor, to Phase 3 evaluation in women with ER positive advanced breast cancer.
Dr. Roth served in multiple leadership roles at Pfizer, where he was a vice president in the company’s oncology business unit. He joined Pfizer from Wyeth, where he held the role of assistant vice president, clinical research & development and global therapeutic area director of hematology. During his tenure at Pfizer and Wyeth, Dr. Roth also co-chaired Pfizer’s oncology research and development board and served on several oncology and hematology R&D leadership teams and governance committees.
Prior to joining the pharmaceutical industry, Dr. Roth’s experience included over 10 years in research and clinical practice as an academic hematologist, and he had been on the full time faculty at Harvard Medical School and Beth Israel Deaconess Medical Center in Boston.
Dr. Roth received his B.S. from the Massachusetts Institute of Technology and his M.D. from Harvard Medical School in the Harvard-M.I.T. Division of Health Sciences and Technology, where he remains on the Affiliated Faculty.
