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Zero Block Society supports harm reduction efforts related to the opioid crisis and focuses on the well-being of frontline harm reduction workers. The organization facilitates the Harm Reduction Workers Guild, which provides weekly meetings for workers to share expertise, voice experiences, and build a supportive community of harm reduction
practitioners. Zero Block Society offers training and resources ranging from basic Naloxone instruction to assistance in establishing overdose prevention sites and broader harm reduction programs. It also provides consultation services and keynote speaking related to harm reduction practices. In addition, the organization conducts community outreach activities such as care and grief support circles and educational talks at various institutions to promote sustainable crisis response and harm reduction knowledge.