Company Performance Metrics
- Nathaniel Wang: Co-Founder and Chief Executive OfficerPast Role: Viridos, Head of the RNA Medicines Business Unit
- Kathy Fernando: Chief Business OfficerPast Role: Pfizer, Senior Vice President and Global Head of Pfizer Ignite
Replicate Bioscience is a clinical-stage biotechnology company developing self-replicating RNA (srRNA) technology to enhance the effectiveness of RNA-based therapeutics beyond traditional mRNA approaches. Its platform is designed to deliver stronger biological activity, more durable immune responses, and an improved therapeutic index. The company’s
lead program, RBI-4000, an srRNA-based rabies vaccine, has shown protective immunity at lower doses than any mRNA or srRNA vaccine reported to date in Phase I studies. Backed by Apple Tree Partners, Replicate is building a diverse pipeline of srRNA vaccines and therapeutics supported by a proprietary, customizable viral vector library. With extensive expertise in srRNA and integrated development capabilities, the company aims to broaden the application of RNA therapies across infectious diseases, immunology, and immuno-oncology.