cheminformatics workflows into a single modular stack. Users can generate analog families under design constraints, evaluate binding and safety signals, and prioritize candidates using multi-signal scoring. The system produces audit-ready artifacts such as candidate tables, Codex logs, and narrative reports that document what changed, why it matters, and suggested next experiments. Its AEON layer adds decision support by tracking design rationales, summarizing trade-offs, and recommending subsequent design moves. Genesis Molecular Engine serves research teams and partners seeking computational support for rational candidate selection and wet-lab planning.