Company Overview

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Founded:
2003
Headquarters:
San Diego, CA
IPO:
Went Public on Apr 17, 2014
Stock:
VTL
Categories:
Biotechnology, Health Care
Description:
Vital Therapies is a biotech company focused on developing a cell-based therapy targeting the treatment of acute liver failure.

Detailed Description

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Vital Therapies, Inc. is a biotherapeutic company focused on developing a cell-based therapy targeting the treatment of acute liver failure. Our product candidate, the ELAD® System, or ELAD, is a bio-artificial liver therapy that operates outside the body, or extracorporeal, and is designed with the proposed intent to allow the patient’s own liver to regenerate to a healthy state, or to stabilize the patient until liver transplant. ELAD is an allogeneic cellular therapy system incorporating our human liver-derived C3A cells contained in four hollow fiber cartridges that are combined with a single use customized disposable set and a reusable bedside unit. Data from ELAD clinical studies has shown trends that may indicate a potential to increase survival rates in patients with acute liver failure. ELAD has received orphan designation in the United States and Europe for the treatment of acute liver failure. Prior to the initiation of our ongoing Phase III clinical trial program, more than 150 subjects have received ELAD therapy in seven clinical trials and through a compassionate use program, which we believe collectively suggests a promising therapeutic profile. We are currently initiating three Phase III clinical trials in various acute liver failure conditions. In March 2013, we initiated VTI-208, a Phase III randomized, controlled clinical trial in 200 subjects with alcohol-induced liver decompensation. In the fourth quarter of 2013, we intend to initiate two additional Phase III randomized controlled trials, VTI-210, in 120 subjects with acute alcoholic hepatitis, and VTI-212, in 126 subjects with fulminant hepatic failure.

Current Team (9)

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Past Team (1)

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Funding Rounds (7) - $177.8M

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Board Members and Advisors (5)

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Investors (1)

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Offices/Locations (1)

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  • Headquarters

    15010 Avenue of Science

    Suite 200

    San Diego, CA 92128

    USA

News (8)

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Images (1)

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  • Cc209eec4a0638c8ce37e132cc3157fd