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General Information

Websiteskylineventures.com
Phone650-462-5800
Employees7
Founded1997

Funds

Offices

Palo Alto Office
525 University Avenue
Suite 520
Palo Alto, CA, 94301
USA
Waltham Office
1050 Winter Street
Suite 1000
Waltham,, MA, 02451
USA

People

Managing Director
Founder
Managing Director
Managing Director

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Skyline Ventures

Skyline Ventures, formed in 1997, is a nationally-known venture capital firm that specializes in investing in outstanding product-focused healthcare companies. Their areas of expertise include small molecule and protein therapeutics; medical devices; diagnostics; and technologies that facilitate drug discovery and life science research.

They all have MD or PhD degrees, and hands-on operating experience in various start-up healthcare companies that later went public. As a result, they are known for the value they offer their companies, as board members and shareholders. They are also known for being fundamental, extremely patient investors.

The days when momentum investing drove the public biotechnology markets are long gone, and they are glad that they are. The public markets demand data, not dreams. As a result, it is data that drives their decision process. In considering a new investment, they focus on whether there is adequate proof of principle to believe that the company’s products will work.

In therapeutics, for example, they look closely at whether the biochemistry, animal models and any human data make it more probable than average that the product will eventually prove to have an important therapeutic benefit. The size of the potential market and the quality of the management or founding team are critical in their evaluation as well.

Skyline Ventures are value and return driven, more than driven by the stage of the investment. Most often they lead or co-lead a company’s first or second institutional venture round, but have previously helped found companies and invested in PIPEs and leveraged buyouts.

In October 2007, they completed raising Skyline V, which has $350 million in committed capital. They have approximately $800 million under management. They target investments of $15-35 million per portfolio company over the life of the company.

Milestones

Investments

Company Date Round Size Participants
Calypso Medical 11/09Series E$50M4
Proteon Therapeutics 5/09Series B$50M8
SpinalMotion 2/09Series C$500k4
Tetraphase Pharmaceuticals 8/08Series A$15M5
InteKrin 8/08Series C$18.5M7
NovaSys 5/08Unattributed$49.5M10
Concert Pharmaceuticals 4/08Series C$37M12
Proteon Therapeutics 9/07Series A$12M4
Satiety 7/07Series D$30M6
MAP Pharmaceuticals 3/07Series D$50M6
Sirtris Pharmaceuticals 12/04Series A$13M5
Applied Genetics Technologies Corporation 11/03Series B$27M4

Videos

Sources

  1. Calypso Medical Technologies, Inc.: Series E $50M (onbiovc.com) [edit]
  2. Proteon Therapeutics Completes Second Closing of Equity Financing (proteontherapeutics.com) [edit]
  3. VentureBeat (venturebeat.com) [edit]
  4. Equity Help Desk (equityhelpdesk.com) [edit]
  5. InteKrin raises $18.5M for continued work on diabetes drug (deals.venturebeat.com) [edit]
  6. Novasys Medical takes $49.5M for women’s medical device (deals.venturebeat.com) [edit]
  7. Capital Funding Report [edit]
  8. PROTEON THERAPEUTICS COMPLETES $12 MILLION FINANCING AND HIRES CFO (proteontherapeutics.com) [edit]
  9. Satiety pulls in $30M for obesity device (venturebeat.com) [edit]
  10. MAP Pharma raises $50M for respiratory and CNS disease treatments (deals.venturebeat.com) [edit]
  11. Sirtris closes $13 million financing (boston.bizjournals.com) [edit]
  12. Company Overview (agtc.com) [edit]
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Last Edited 11/2/09

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