Back to Mobile View
Subscribe to the CrunchBase Daily for the latest on Fundings, Acquisitions, and Startup Events

General Information


Kalamazoo, USA
350 E. Michigan Avenue
Suite 205
Kalamazoo, MI, 49007


Chief Operating Officer
President and CEO
Chief Medical Officer


TOTAL $9.56M
Series A, 6/2008
Southwest Michigan First, Investment Arm
Triathlon Medical Venture Partners
Hopen Therapeutics
Partial Close, 6/2010
Series B, 10/2012
Hopen Life Science Ventures
Triathlon Medical Venture Partners
Southwest Michigan First, Investment Arm
Debt, 5/2012
Debt, 10/2013


Tolera Therapeutics

Tolera Therapeutics Inc., founded under the scientific and medical direction of Maria Siemionow, M.D., Ph.D., D.Sc., is a spin-off of the Cleveland Clinic focused on bringing more specific, and safer therapies to market with competitive speed.

The company’s technology stems from immune modulation and transplant research done at the Cleveland Clinic under the leadership of Dr. Siemionow, an internationally recognized leader in the fields of microsurgery and transplantation. In addition to her surgical skills, she has focused her research efforts on the development of therapies to promote life-long acceptance of organ and tissue transplants, while reducing or eliminating the need for chronic immunosuppression therapies and their dangerous side effects. In addition, Dr. Siemionow’s efforts have led to new discoveries in immune system modulation. She has authored and contributed to over 180 peer reviewed articles on transplantation, immune suppression and organ tolerance.

Recent Milestones



Tolera Therapeutics screenshot
Above: Homepage
Uploaded: 5/27/09


  1. Capital Funding Report [edit]
  2. SEC ( [edit]
  3. SEC ( [edit]
  4. Tolera Therapeutics closes Series B-3 financing, raises $5.5 million to submit Phase 3 Special Protocol Assessment for its immune targeting biologic drug in kidney transplantation PR Newswire ( [edit]
  5. SEC ( [edit]
Edit This Page
Last Edited 12/30/13

Revision History RSS Picture


Share this page on Twitter or Facebook:
Or copy this code to embed a widget: customize »

External Links

CrunchBase API


Become a Sponsor
Terms of Service | Privacy Policy | Licensing Policy