| Website | prexainc.com |
| Category | BioTech |
| Phone | 203.858.3428 |
| egraham@prexainc.com | |
| Employees | |
| Founded | 2006 |
| TOTAL | $10.2M |
| VENTURE FUNDING TOTAL | $10.2M |
| Venture Round, 4/11 | $3.2M |
| Series B, 5/11 Advent Venture Partners Shire | $7M |
Prexa, founded in 2006, is developing oral small molecule monoamine reuptake inhibitors that act most potently at the dopamine transporter. By safely enhancing dopamine activity and, to a lesser extent norepinephrine activity, Prexa intends to improve upon current treatments for ADHD, depression and Parkinson’s disease.
Prexa’s proprietary compound portfolio consists of highly differentiated reuptake inhibitors with unique dopamine-preferring neurotransmitter selectivity profiles. Prexa’s lead compound, PRX-12251, is a triple reuptake inhibitor that blocks dopamine, norepinephrine and serotonin transporters. PRX-12251 is entering IND-enabling studies. Prexa’s mono and dual reuptake inhibitors are targeted for partnerships with leading biotechnology and pharmaceutical companies.