Idera Pharmaceuticals
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Idera Pharmaceuticals, Inc., a biotechnology company, discovers and develops DNA- and RNA-based drug candidates for the treatment of infectious diseases, autoimmune and inflammatory diseases, cancer, and asthma and allergies, and for use as vaccine adjuvants. The company designs and creates proprietary Toll-Like Receptors (TLR) to modulate immune responses, including TLR agonist, a compound that stimulates an immune response through the targeted TLR; and TLR antagonist, a compound that blocks activation of an immune response through the targeted TLR. Its drug candidates include IMO-2125, a TLR9 agonist, which is in Phase 1 clinical trial for hepatitis C virus infection; and TLR7, 8, and 9 agonists that are in research stage for viral diseases. The company also develops IMO-3100, a dual TLR7/TLR9 antagonist, which is in preclinical development stage for autoimmune and inflammatory diseases, such as lupus, rheumatoid arthritis, multiple sclerosis, psoriasis, and colitis. In addition, its drug candidates also comprise TLR7 and TLR8 agonists that are in research stage for solid tumor cancers. The company has a licensing and collaboration agreement with Merck KGaA to research, develop, and commercialize TLR9 agonists for the treatment of cancer, excluding cancer vaccines; a license and research collaboration agreement with Merck & Co., Inc. to research, develop, and commercialize therapeutic and prophylactic vaccine products containing its TLR7, 8, and 9 agonists in the fields of cancer, infectious diseases, and Alzheimerâ€™s disease; and a research collaboration and option agreement, and a license, development, and commercialization agreement with Novartis International Pharmaceutical, Ltd. to discover, develop, and commercialize TLR9 agonists for the treatment of asthma and allergies. The company was founded in 1989 and is based in Cambridge, Massachusetts.

Recent Milestones
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Idera Pharmaceuticals — Struggling Idera Pharmaceuticals raises $7M (11/12/12)

Posted 11/12/12 at 6:50pm via masshightech.com
Idera Pharmaceuticals received $9.5M in Venture Round funding. (11/7/11)

Posted 11/7/11 at 6:16pm via masshightech.com
Idera Pharmaceuticals — Idera to net $3.8M milestone pay from Merck (8/27/10)

Posted 8/30/10 at 1:55am via masshightech.com
Idera Pharmaceuticals received $4.3M in Venture Round funding. (1/19/10)

Posted 1/20/10 at 1:34am via masshightech.com
Went public with stock symbol NASDAQ:IDRA.

Posted 1/20/10 at 1:35am
Idera Pharmaceuticals added Sudhir Agrawal as President and CEO.

Posted 1/20/10 at 1:34am
Idera Pharmaceuticals added Louis J. Arcudi as CFO.

Posted 1/20/10 at 1:34am